Oncotrex 5 Tablet is a medicine used for treatment of cancer in various parts of the body such as breasts, head, neck, lungs, blood, bone, lymph, and uterus. It is also used to treat rheumatoid arthritis, severe and uncontrolled psoriasis, and Crohn’s disease.
Oncotrex 5 Tablet may be used alone or in combination with other medicines. You should take it exactly as your doctor has advised. Taking too much of it can cause serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. You should avoid consumption of alcohol while taking this medicine as it may increase your risk of liver damage.
The most common side effects of this medicine are ulcerative stomatitis, hairloss, low blood cell count, increased liver enzymes, nausea, and abdominal distress. Your doctor may advise you to take folic acid to reduce some of these. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. This medicine may lower your ability to fight infections and lead to problems with your blood, liver, or kidneys. Your doctor may perform several tests such as blood tests, X-rays, and physical examinations both before and during treatment with this medicine to check for these.
Before taking it, tell your doctor if you have problems related to the stomach, liver, or kidney, or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding as it may harm the baby.
Oncotrex 5 Tablet works by slowing the growth of cancer cells in the body. It is used to treat a wide range of cancers such as acute leukemias, non-Hodgkin’s lymphoma, and solid tumors found in breast, lung, bladder, head and neck as well as cervical, ovarian and testicular cancer. It may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
Side effects of Oncotrex Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Oncotrex
Ulcerative stomatitis
Nausea
Abdominal pain
Increased liver enzymes
Hair loss
Decreased blood cells (red cells, white cells, and platelets)
How to use Oncotrex Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Oncotrex 5 Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Oncotrex Tablet works
Oncotrex 5 Tablet inhibits enzymes (dihydrofolate reductase), prevents cell division and leads to anti-inflammatory actions. Oncotrex 5 Tablet kills cancer cells by preventing them from making DNA. Oncotrex 5 Tablet can help control psoriasis by retarding the production of skin cells and suppressing inflammation. Oncotrex 5 Tablet may treat rheumatoid arthritis by suppressing the immune system, preventing it from attacking the body's cells. This helps reduce the inflammation that causes swollen and stiff joints in rheumatoid arthritis, or damage to bowel in Crohn's disease.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Oncotrex 5 Tablet.
Pregnancy
UNSAFE
Oncotrex 5 Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding
UNSAFE
Oncotrex 5 Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Oncotrex 5 Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Oncotrex 5 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Oncotrex 5 Tablet may be needed. Please consult your doctor. Regular monitoring of kidney function test is advised while you are taking this medicine.
Liver
CAUTION
Oncotrex 5 Tablet should be used with caution in patients with liver disease. Dose adjustment of Oncotrex 5 Tablet may be needed. Please consult your doctor.
What if you forget to take Oncotrex Tablet?
If you miss a dose of Oncotrex 5 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.